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Immunobiology and HIV, 2008.
An analysis of the mechanisms involved in HIV infection and the role of chemokines in suppression of HIV replication.
2,060 words (approx. 8.2 pages), 8 sources, MLA, $ 64.95
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Abstract
This paper analyzes the relationship between immunobiology and HIV. It analyzes the research in an attempt to understand the mechanisms involved in HIV infection and in the operation of various related biological effects. The paper then addresses the role of the chemokine MIP-1 beta, among others, in T cell mediated suppression of HIV replication.
From the Paper
"Patke, Green, and Shearer examine the role of beta-chemokines and their chemokine receptor on HIV B lymphocyte function. To test this interaction, the researchers used highly purified normal human B cells from seronegative donors, isolating them by adherence to CD19-coated beads. They then treated IL-4 plus anti-CD40-activated B cells with recombinant gp120 (10 ng/ml) before exposure to beta chemokines or receptor. At that stage, cyclic nucleotide generation was assessed at six hr, DNA synthesis at day threem and IgM production on day seven. Also, cell surface marker expression was determined by flow cytometric analysis using the Coulter EPICS-XL. What the researchers found was that there ia a role for MIP-1 beta and RANTES on the early B cell events of proliferation, cyclic nucleotide generation, and cell surface marker receptor modulation in opposition to the beta chemokine receptor, CCR5. the researchers also note that the ability to regulate early B cell events might be a targeted area in the development of novel designer molecule therapeutic approaches to AIDS, though further research is needed finally to demonstrate this possibility."
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Marine Species Conservation, 2008.
This paper explores the Elkhorn Coral and what can be done to rescue this vulnerable marine species.
1,366 words (approx. 5.5 pages), 6 sources, MLA, $ 45.95
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Abstract
The paper discusses the precarious position of the Elkhorn Coral and identifies the features of an effective conservation policy at the national and/or international level. This includes keeping human beings and animals away from the reefs, developing non-intrusive bulwarks as a protection from large-scale hurricanes and distancing industrial works and run-off from the reefs. The paper concludes that an effort should be undertaken to build up an international coalition of environmentalists and sympathetic policy-makers who can remind political elites around the globe of under-reported marine species such as the Elkhorn Coral.
From the Paper
"One of the most obvious problems currently bedeviling the Elkhorn Coral is its susceptibility to disease. According to the United States Office of Protected Resources, the Elkhorn Coral has had problems with rampant disease since the dawn of the 1980s (para.4). Indeed, by the middle-1980s, scientists were becoming increasingly alarmed by the spread of calicoblastic neoplasms or cancerous lesions among Elkhorn Coral colonies in the Florida region - most notably among those colonies housed at the Key Largo National Marine Sanctuary in Key Largo, Florida (Peters, 895)."
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Drug Trial for Cancer Medication, 2008.
This paper discusses the drug Zometa that is used as a support medication for treating symptoms of cancer.
2,427 words (approx. 9.7 pages), 11 sources, MLA, $ 74.95
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Abstract
In this article, the writer notes that the research and development on a new drug is expensive and time-consuming, followed by a lengthy trial and a lengthy approval process by the Food and Drug Administration (FDA). The writer points out that Zometa was approved for the treatment of hypecalcemia, a common metabolic complication associated with cancer. The writer discusses that research into the action of the bisphosphonate zoledronic acid (marketed as Zometa) was undertaken to gain FDA approval for use of the drug for the treatment of osteolytic bone metastases, and research is also under way for use of the drug for other purposes as well. The writer concludes that so far, approval has only been given for its use in treating cancer patients with bone metastases, though there are indications that it will be valuable for breast cancer patients facing other difficulties.
Outline:
Introduction
Medical Problems to be Addressed
Drug Action
Approval of the Drug
Conclusion
From the Paper
"Hypercalcimia of malignancy is considered the most common life-threatening metabolic complicastin of malignancy. It affects some 10 to 20 percent of patients with advanced cancer, varying widely with the type of cancer involved. It occurs most often in patients with multiple myeloma and carcinomas of the lung, breast, kidney, and the head and neck. Antihypercalcemic therapy is used, but median survival under these conditions has been found to be 30 days. Certain symptoms diminish the quality of life for these patients, such as nausea, vomiting, and altered mental states. HCM can also produce renal failure. Patients with bone metastases can also develop HCM. Factors that mediate hypercalcemia stimulate excess bone resorption and the release of calcium from the bone matrix, meaning that patients experience bone loss, a weakened bone structure, and higher circulating calcium levels. Bisphosphonates inhibit bone resorption and are the most effective therapy for HCM. Pamidronate has been one of the most commonly used treatments for HCM."
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Iron Deficiency in Iran, 2008.
This paper discusses social determinations of health and measures to reduce the prevalence of iron deficiency, concentrating on Iran.
1,338 words (approx. 5.4 pages), 10 sources, APA, $ 44.95
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Abstract
In this article, the writer notes that iron deficiency is an issue for developing and industrialized countries. Iron deficiency involves both modifiable risk factors and the social determinants of health. The writer maintains that part of the problem is that measures of iron deficiency are inconsistent while another part of the problem relates to varying combinations of nutrients or just one nutrient being used in isolation. The writer discusses that Iran is a developing country where the prevalence has been heavily reduced, but it is possible that if the determinants of health were used as variables, the prevalence could be eliminated. The writer notes that the nutrition the mother and child receives during the period when the child is six to 12 months of age has implications for the entire life span but must be situated in terms of the overall conditions of socioeconomic position and the culture.
Outline:
Abstract
Introduction
Rationale
Literature Review
Description of Methodology
References
From the Paper
"Iron deficiency is a problem in both developing and industrialized countries. The objective is to demonstrate that whether the issue of irony deficiency is located in the Third World or in affluent nations, it is based in modifiable risk factors. The hypothesis is that the problem with addressing iron deficiency is related to the determinants of health since, if nutritional supplementation is aimed only at the first priority, then entire aspects of the child's development will inevitably be neglected. The research question is: In a country such as Iran where prevalence has been reduced to a moderate level, can that prevalence of iron deficiency be further reduced by using the determinants of health as measures?"
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Brain Cancer Rehabilitation, 2008.
This paper discusses the different treatments and therapies available to aid in rehabilitation following brain cancer.
1,933 words (approx. 7.7 pages), 8 sources, MLA, $ 61.95
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Abstract
In this article, the writer discusses that brain cancer, unlike other cancers, possesses certain characteristics that make physical therapy treatment similar to that of treatments of other brain injuries such as strokes or trauma. The writer notes that while the prospect and dread associated with brain tumors is understandable, timely diagnosis, surgery, post-operative cancer eradication and expedient physical therapy can restore functionality, independence and productivity. The writer looks at the different kinds of brain cancer and then examines diagnosis matters and different types of treatment and therapy.
Outline:
Overview
Types of Brain Cancer
Pathogenesis
Signs and Symptoms
Diagnosis
Treatment
Impairments, Functional Limitations and Disabilities
Physical Therapy Treatment
Conclusion
From the Paper
"Clinical suspicion of a brain tumor and possible localization through clinical neurological physical findings should lead to a means of visualizing the central nervous system in the least invasive manner possible. The gold standard for diagnosis would ideally be biopsy of the tumor; however, such procedures may jeopardize the patient's life, if at all impractical for most tumors lying deep within the brain parenchyma. However, these may be indicated when diagnostic imaging fails to convey a definite impression and a biopsy, with all risks and benefits carefully weighed and preliminary medical treatment to prevent brain herniation undertaken. Moreover, a biopsy of the lesion must be able to show that in being done, it will affect subsequent medical treatment."
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Gestational Diabetes and Pregnancy-Induced Hypertension, 2008.
This paper discusses gestational diabetes and looks at whether there is a connection with pregnancy-induced hypertension.
1,838 words (approx. 7.4 pages), 9 sources, APA, $ 58.95
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Abstract
In this article, the writer notes that gestational diabetes affects only a very small percentage of all pregnant mothers. The writer further notes that pregnancy-induced hypertension is found in about the same proportion of pregnant mothers as is gestational diabetes. The writer points out that weight gain during pregnancy predicts very high risk for gestational diabetes, along with other problems such as pregnancy-induced hypertension, Cesarean section and stillbirth. The writer provides a literature review and discusses whether there is a link between gestational diabetes and pregnancy-induced hypertension so that they can be treated together. The writer maintains that the treatment of women with gestational diabetes, along with health teaching, which involves dietary advice, blood glucose monitoring, and insulin therapy, results in a reduction of serious perinatal outcomes such as death or bone fracture. Other benefits include improved health-related quality of life among women with gestational diabetes, both during the antenatal period and three months after birth, as well as a possible reduction in the incidence of postnatal depression.
Outline:
Introduction
Background
Literature Review
Analysis
From the Paper
"Haakova and Cibula found in their retrospective study with data obtained from medical records that women who have polycystic ovary syndrome, which is a common endocrine disorder, that there are no important differences in the prevalence of gestational diabetes or of pregnancy-induced hypertension. Even though the two groups in the study were matched for age, weight, family history, and patient history, both gestational diabetes and hypertension were similar for those groups. However, as these researchers note, a high incidence of pregnancy induced hypertension has been found in several other studies of women with polycystic ovary syndrome, so that there may be a link between hyperinsulinaemia and hypertension during pregnancy.
"Lifestyle interventions also constitute the primary treatment for gestational diabetes."
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How Does Evolution Really Work?, 2008.
An analysis of the theory behind evolution and natural selection, according to Charles Darwin.
878 words (approx. 3.5 pages), 4 sources, MLA, $ 31.95
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Abstract
This paper discusses the concepts behind Charles Darwin's theory of evolution. It describes the four processes of evolution according to Darwin, while specifically focusing on hummingbirds from Ecuador as a great example of a species in which the gene pool has prepared for long-term survival. The paper also briefly mentions the arguments against Darwin.
Outline:
Summary
Discussion
From the Paper
"Although Darwin's theories are accepted by the majority of the scientific community, there are still those that put it in doubt in spite of the evidence that has arisen from the study of fossils and genetic material. As he himself had anticipated in The Origin of Species, "That many and grave objections may be advanced against the theory of descent with modification through natural selection, I do not deny" (Darwin ch. 14, para. 2, line 1). In his time, Darwin's theories caused outrage since they challenged the traditional views of Church and society. Natural selection was contrary to both the notion of human domination and the concept of divine intervention. The same fear persists until this day. In some societies, the concept of evolution as conceived by Darwin is still in conflict with religious beliefs. For many, the main obstacle is the fact that natural selection is just a theory and no scientific proof as such is available ("Evolutionary Science"). Just as with gravitation we see the effects and not gravitation itself, with natural selection we see its effects but research still needs to be performed to fully explain its mechanisms."
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The Use of Primates in Bio-medical Research, 2008.
An analysis of whether or not bio-medical testing on primates is worthwhile, despite the drawbacks.
2,021 words (approx. 8.1 pages), 11 sources, APA, $ 64.95
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Abstract
This paper examines to what extent bio-medical research is aided by the testing of primates. It provides an exploration into disease prevention using primates, discusses embryonic research and cloning and shows how the human behavioral processes in the mind can be disclosed through primate testing. The paper concludes that the literature is inconclusive and the testing of primates must be seriously re-examined.
From the Paper
"The hypothesis of this paper was that primate testing does benefit human beings enough to justify the use of these animals in projects. Ultimately though, the material uncovered does not support this thesis (except in limited cases) and it calls into question the determination of some in the scholarly community to resolutely persist with such testing. Furthermore, questions such as whether or not such testing offers insight into the fight against disease, the study of human cloning and embryonic research, and the study of the human mind, all failed to deliver clear-cut answers; in some respects, the use of these creatures works, and in other areas the conclusion is much more uncertain."
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Bottle-Feeding Research, 2008.
This paper provides an analysis of an article about bottle feeding entitled "Factors Contributing to Preterm Infant Engagement During Bottle-Feeding", by S.M. Thoyre and R.L. Brown.
824 words (approx. 3.3 pages), 1 source, MLA, $ 29.95
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Abstract
In this paper the writer discusses the article "Factors Contributing to Preterm Infant Engagement During Bottle-Feeding," that appeared in the September/October 2004 issue of the Journal Nursing: Official Journal of the Eastern Nursing Research society and the Western Institute of Nursing. The writer notes that this journal is a peer-reviewed publication. The writer points out that this study was well written and maintains that all of its points and conclusions were clear and fully explained and supported. Further, the writer declares that the interpretations were appropriate, led to logical conclusions and appeared to be unbiased. The writer concludes that the article increases the writer's knowledge about bottle-feeding and answers many questions about the importance of an infant being engaged during the feeding process.
Outline:
Source
Abstract
Research Problem
Literature Review
Theoretical Framework
Variables
Hypothesis
Design
Sample
Data Collection
Study Procedures
Ethical Consideration
Data Analysis
Discussion and Interpretation of Findings
Application to Nursing Practice
Presentation
From the Paper
"The research was clearly described as a cross-sectional study conducted in the Midwest over a period of six months. There was no manipulation of the independent variables; rather, the manner in which the data was recorded was altered to make the data more meaningful. A lot of attention was given to detail in this study and efforts were made to control for potential confounding factors."
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Stem Cell Research, 2008.
This paper argues for the continuation of stem cell research.
995 words (approx. 4.0 pages), 6 sources, APA, $ 35.95
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Abstract
The paper looks at the debate regarding whether human embryos possess "human rights" and thus the right to live in the fully developed human sense. The paper discusses this ethical and controversial issue and strongly contends that stem cell research must be allowed to continue unabated while trying to find ways to circumvent the ethical dilemmas that hinder it.
Outline:
Introduction
Opposing Viewpoints
Pro Viewpoints
Conclusion
From the Paper
"In spite of these controversial issues, stem cell research must be allowed to continue unabated not only to find practical application in cell and organ transplantation and regenerative medicine, but also to alleviate the emotional burdens of all those involved in a patient's suffering. Embryonic stem cell research involves growing stem cells derived directly from human embryos and is the present method employed in growing stem cell colonies. Still in development is non-embryonic stem cell research, which seeks to circumvent the heated debates regarding whether human embryos possess "human rights" and thus the right to live in the fully developed human sense (Cort, 2005)."
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The Evolution and Distribution of the Crocodile, 2008.
This paper explores the adaptive and biological alterations of the crocodile species over millions of years and analyzes its prehistoric, historic and recent distribution patterns.
2,445 words (approx. 9.8 pages), 9 sources, APA, $ 74.95
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Abstract
This paper explains that crocodiles, which are now cold-blooded reptiles that seek water, were once, during their earliest prehistoric days, warm-blooded creatures that walked on land. The author points out that this transformation is observable in changes in the Crocodilian body over time. The paper relates that it is not known why crocodiles grew to accommodate to a water-based environment, but their adaptations helped them survive the Ice Age. The author states that, having once dominated both arid and water regions, today, crocodiles gravitate toward regions, which provide access to water; however, warming global climate conditions and human interference have reduced their numbers to dangerous levels. The paper relates that several small communities of crocodiles living on the southern edge of the Sahara Desert in Africa may be a sign of things to come.
Table of Contents:
Outline
Introduction
The Developmental History of Crocodiles
Motivators for Adaptation
Distribution Over the Ages
Conclusion
From the Paper
"The reason for near-extinction of the Florida Crocodile, the Cuban Crocodile and other Crocodilian species is typically owing to environmental and climate changes (i.e. loss of ample wetlands) and loss of habitat due to human development. In Florida in particular, the building of human homes on areas which were once crocodile habitats have affected the nesting range and distribution of crocodiles. True to their modern adaptations and features, crocodiles gravitate towards the remaining wet, swampy regions. However, awareness of their vulnerability has lead to recent conservations acts that have been mostly successful."
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The E-Coli Bacillus, 2008.
This paper discuses the e-coli bacillus, which has been responsible for a profusion of e-coli outbreaks in recent years.
850 words (approx. 3.4 pages), 10 sources, MLA, $ 30.95
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Abstract
This paper explains that the e-coli bacillus is a microbe about which much is known but has defied efforts to stamp out its unpleasant impact upon human health. The author points out that these extraordinarily tiny cells are invisible to the naked human eye and can accumulate in vast quantities in food preparation areas without individuals being aware of them. The paper relates that e-coli cells are prokaryotic and distinguished by a single, circular chromosome; such cells also contain DNA as plasmids. The author states that, in simple cases of e-coli poisoning, rehydration is essential; however, there is no evidence that antibiotics improve the course of the disease and/or expedite recovery and anti-diarrheal agents are strongly discouraged. The paper concludes that this tiny "bug" certainly seems resilient enough to cause human beings misery for some time to come.
From the Paper
"The living environment and the reproductive process of the e-coli cell are also interesting. Simply put, e-coli most commonly flourish in the intestines of warm-blooded animals. In terms of reproduction, the process is simply one of binary fission, with the circular DNA chromosome replicated. The cell splits into two identical cells with each cell having the same DNA; it should be pointed out that, during the fission process, the identical chromosomal material attaches itself to different parts of the cell membrane so that "replicate" material is firmly anchored where it needs to be when the cell begins to pull apart and halve."
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